Ball Mill Pm400 Standard Operating Protocol

Patent application title pyrazolo3,4-bpyridine compound, and its use as a pde4 inhibitor.Containing 10 fines e.G.990 mg, 99 ww in a teflon polytetrafluoroethene pot in a mikro-dismembrator ball-mill but without a ball bearing at speed ca.2000-2500 rpm for about 4 hours at each blend concentration.The mikro-dismembrator.